Acting in tandem

Bioinformatic prediction and experimental validation of a microRNA-directed tandem trans-acting siRNA cascade in Arabidopsis.

Small RNAs play pivotal roles in regulating gene expression in higher eukaryotes. Among them, trans-acting siRNAs (ta-siRNAs) are a class of small RNAs that regulate plant development. The biogenesis of ta-siRNA depends on microRNA-targeted cleavage followed by the DCL4-mediated production of small RNAs phased in 21-nt increments relative to the cleavage site on both strands. To find TAS genes,...

A Mathematical Model for Multiple-Load AGVs in Tandem Layout

Reducing cost of material handling has been a big challenge for companies. Flexible manufacturing system employed automated guided vehicles (AGV) to maintain efficiency and flexibility. This paper presents a new non-linear mathematical programming model to group n machines into N loops, to make an efficient configuration for AGV system in Tandem layout. The model minimizes bot...

Acting in Character

In this context, it is not the personality of the actor that interests us, but the personality of the character he or she portrays. Thus, when we say that an actor is “in character,” we mean that the actor is behaving in accordance with a personality created by an author, shaped by a director, and assumed by an audience, for purposes of a particular performance. A good actor creates and communi...

Long-acting sulfonylureas -- long-acting hypoglycaemia.

TANDEM: matching proteins with tandem mass spectra.

SUMMARY Tandem mass spectra obtained from fragmenting peptide ions contain some peptide sequence specific information, but often there is not enough information to sequence the original peptide completely. Several proprietary software applications have been developed to attempt to match the spectra with a list of protein sequences that may contain the sequence of the peptide. The application TA...